Error trying to upgrade

[Doctor Who]

I'm getting the following error when trying to upgrade my installed ports:

sudo port upgrade installed -f
--->  Activating libtool-devel @2.3a_0
Error: Activating libtool-devel @2.3a_0 failed: Image error:
/opt/local/bin/glibtool is being used by the active libtool port.
Please deactivate this port first, or use the -f flag to force the
activation.
--->  Activating p5-digest-md5 @2.38_0
Error: Activating p5-digest-md5 @2.38_0 failed: Image error:
/opt/local/share/man/man3/Digest::MD5.3pm.gz is being used by the
active perl5.8 port.  Please deactivate this port first, or use the -f
flag to force the activation.

What's the right way to address this?  It appears trying to deactivate
the ports or using '-f' don't work.

Thanks.